• Laser & Optoelectronics Progress
  • Vol. 62, Issue 2, 0209001 (2025)
Dechao Zhao1、*, Qieni Lü2, Huaying Wang1、3、4, Di Zhen1, and Zhongwei Sun1
Author Affiliations
  • 1School of Mathematics and Physics, Hebei University of Engineering, Handan 056038, Hebei , China
  • 2School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China
  • 3Hebei Computational Optical Imaging and Photoelectric Detection Technology Innovation Center, Handan 056038, Hebei , China
  • 4Hebei International Joint Research Center for Computational Optical Imaging and Intelligent Sensing, Handan 056038, Hebei , China
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    DOI: 10.3788/LOP241293 Cite this Article Set citation alerts
    Dechao Zhao, Qieni Lü, Huaying Wang, Di Zhen, Zhongwei Sun. Diagnostic Method for Exhaled Aerosol Particle Field Based on Digital In-Line Holography[J]. Laser & Optoelectronics Progress, 2025, 62(2): 0209001 Copy Citation Text show less

    Abstract

    The particle size and distribution characteristics of exhaled aerosol particle fields are related to the health status. This study proposes a diagnostic method for exhaled aerosol particle fields using coaxial digital holography. A connected domain method was employed to extract particle sizes from the reconstructed images of exhaled aerosol particle field holograms, determine particle size distributions, and calculate statistical parameters (D10, D32, D43, and DN50). The method was tested on 14 healthy volunteers and 10 infected patients to obtain the distribution and average values of two sets of particle size statistical parameters. The detection accuracy within the distribution range of particle size statistical parameters was calculated, and benchmark points for each statistical parameter were obtained. Using the four benchmark points and average particle size statistical parameters as indicators, six test volunteers were tested. By minimizing the accuracy and coefficient of variation, the Sauter mean diameter is identified as the optimal criterion for assessing the health status, achieving a detection accuracy rate of over 80%. This study introduces an optical method for the preliminary diagnosis of influenza through the analysis of exhaled aerosol particle fields.
    Dechao Zhao, Qieni Lü, Huaying Wang, Di Zhen, Zhongwei Sun. Diagnostic Method for Exhaled Aerosol Particle Field Based on Digital In-Line Holography[J]. Laser & Optoelectronics Progress, 2025, 62(2): 0209001
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