Contents
2024
Volume: 14 Issue 2
4 Article(s)
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Microstructured Cantilever Probe on Optical Fiber Tip for Microforce Sensor
Famei WANG, Changrui LIAO, Mengqiang ZOU, Dejun LIU, Haoqiang HUANG, Chao LIU, and Yiping WANG
Benefiting from the great advances of the femtosecond laser two-photon polymerization (TPP) technology, customized microcantilever probes can be accurately 3-dimensional (3D) manufactured at the nanoscale size and thus have exhibited considerable potentials in the fields of microforce, micro-vibration, and microforce sBenefiting from the great advances of the femtosecond laser two-photon polymerization (TPP) technology, customized microcantilever probes can be accurately 3-dimensional (3D) manufactured at the nanoscale size and thus have exhibited considerable potentials in the fields of microforce, micro-vibration, and microforce sensors. In this work, a controllable microstructured cantilever probe on an optical fiber tip for microforce detection is demonstrated both theoretically and experimentally. The static performances of the probe are firstly investigated based on the finite element method (FEM), which provides the basis for the structural design. The proposed cantilever probe is then 3D printed by means of the TPP technology. The experimental results show that the elastic constant k of the proposed cantilever probe can be actively tuned from 2.46 N/m to 62.35 N/m. The force sensitivity is 2.5 nm/μN, the Q-factor is 368.93, and the detection limit is 57.43 nN. Moreover, the mechanical properties of the cantilever probe can be flexibly adjusted by the geometric configuration of the cantilever. Thus, it has an enormous potential for matching the mechanical properties of biological samples in the direct contact mode..
Photonic Sensors
- Publication Date: Jul. 24, 2024
- Vol. 14, Issue 2, 240204 (2024)
Review
Research on Fiber Optic Surface Plasmon Resonance Biosensors: A Review
Qi WANG, Dianyun ZHANG, Yizhuo QIAN, Xiangyu YIN, Lei WANG, Shushuai ZHANG, and Yuyang WANG
Due to the benefits of the high sensitivity, real-time response, no labeling requirement, and good selectivity, fiber optic sensors based on surface plasmon resonance (SPR) have gained popularity in biochemical sensing in recent years. The current research on such sensors is hot in enhancing sensitivity, improving deteDue to the benefits of the high sensitivity, real-time response, no labeling requirement, and good selectivity, fiber optic sensors based on surface plasmon resonance (SPR) have gained popularity in biochemical sensing in recent years. The current research on such sensors is hot in enhancing sensitivity, improving detection accuracy, and achieving the detection of biochemical molecules. The goal of this work is to present a thorough overview of recent developments in the optical fiber SPR biosensor research. Firstly, it explores the basic principles and sensing structures of optical fiber SPR biosensors, focusing on four aspects. Subsequently, this paper introduces three fiber optic surface plasmon biosensors: SPR, localized surface plasmon resonance (LSPR), and long-range surface plasmon resonance (LRSPR). Each concept is explained from the perspective of the basic principles of fiber optic SPR biosensors. Furthermore, a classification of fiber optic SPR biosensors in health monitoring, food safety, environmental monitoring, marine detection, and other applications is introduced and analyzed. Eventually, this paper summarizes the current research directions of SPR biosensors. Meanwhile, it provides a prospective outlook on how fiber optic SPR sensors will develop in the future..
Photonic Sensors
- Publication Date: Jul. 24, 2024
- Vol. 14, Issue 2, 240201 (2024)
Review of Fiber-Optic Localized Surface Plasmon Resonance Sensors: Geometries, Fabrication Technologies, and Bio-Applications
Mengdi LU, Chen WANG, Ruizhi FAN, Ming LIN, Jianye GUANG, and Wei PENG
Localized surface plasmon resonance (LSPR) biosensors, which enable nanoscale confinement and manipulation of light, offer the enhanced sensitivity and electromagnetic energy localization. The integration of LSPR with the fiber-optic technology has led to the development of compact and versatile sensors for miniaturizaLocalized surface plasmon resonance (LSPR) biosensors, which enable nanoscale confinement and manipulation of light, offer the enhanced sensitivity and electromagnetic energy localization. The integration of LSPR with the fiber-optic technology has led to the development of compact and versatile sensors for miniaturization and remote sensing. This comprehensive review explores various sensor configurations, fiber types, and geometric shapes, highlighting their benefits in terms of sensitivity, integration, and performance improvement. Fabrication techniques such as focused non-chemical bonding strategies and self-assembly of nanoparticles are discussed, providing control over nanostructure morphology and enhancing sensor performance. Bio-applications of fiber-optic LSPR (FOLSPR) sensors are detailed, specifically in biomolecular interactions and analysis of proteins, pathogens and cells, nucleic acids (DNA and RNA), and other small molecules (organic compounds and heavy metal ions). Surface modification and detection schemes are emphasized for their potential for label-free and real-time biosensing. The challenges and prospects of FOLSPR sensors are addressed, including the developments in sensitivity, fabrication techniques, and measurement reliability. Integration with emerging technologies such as nanomaterials is highlighted as a promising direction for future research. Overall, this review provides insights into the advancements and potential applications of FOLSPR sensors, paving the way for sensitive and versatile optical biosensing platforms in various fields..
Photonic Sensors
- Publication Date: Jul. 24, 2024
- Vol. 14, Issue 2, 240202 (2024)
Liquid Crystal Based Label-Free Optical Sensors for Biochemical Application
Jieyuan TANG, Zhibin LI, Mengyuan XIE, Yunhan LUO, Jianhui YU, Guojie CHEN, and Zhe CHEN
Biochemical sensors have important applications in biology, chemistry, and medicine. Nevertheless, many biochemical sensors are hampered by intricate techniques, cumbersome procedures, and the need for labeling. In the past two decades, it has been discovered that liquid crystals can be used to achieve the optical amplBiochemical sensors have important applications in biology, chemistry, and medicine. Nevertheless, many biochemical sensors are hampered by intricate techniques, cumbersome procedures, and the need for labeling. In the past two decades, it has been discovered that liquid crystals can be used to achieve the optical amplification of biological interactions. By modifying recognition molecules, a variety of label-free biochemical sensors can be created. Consequently, biochemical sensors based on the amplification of liquid crystals have become one of the most promising sensors. This paper describes in detail the optical sensing principle of liquid crystals, sensing devices, and optical detection technologies. Meanwhile, the latest research findings are elucidated. Finally, the challenges and future research directions are discussed..
Photonic Sensors
- Publication Date: Jul. 24, 2024
- Vol. 14, Issue 2, 240203 (2024)
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