• Laser & Optoelectronics Progress
  • Vol. 61, Issue 20, 2011018 (2024)
Chengfu Gu, Haoran Zhang, Qi Lan, Weiyi Zhang..., Chang Liu and Jianlong Yang*|Show fewer author(s)
Author Affiliations
  • School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
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    DOI: 10.3788/LOP241289 Cite this Article Set citation alerts
    Chengfu Gu, Haoran Zhang, Qi Lan, Weiyi Zhang, Chang Liu, Jianlong Yang. Advances in Depth-of-Focus Extension Methods for Optical Coherence Tomography[J]. Laser & Optoelectronics Progress, 2024, 61(20): 2011018 Copy Citation Text show less

    Abstract

    The clinical applications of optical coherence tomography (OCT) have expanded beyond ophthalmology to include imaging of various body cavities, functional imaging, diagnostic integration, and surgical robotics. Consequently, there is an increasing need to enhance the resolution of OCT to analyze biological tissues at the cellular level and beyond. However, enhancing OCT's lateral resolution typically results in a reduced depth of focus, which complicates the acquisition of a consistent point spread function throughout the imaging range. To address this issue, researchers have developed various strategies for extending the depth of focus, including using Bessel beams, phase masks, dispersion effects, synthetic apertures, computational imaging, multimode interference, and dynamic focusing. Each method employs distinct principles to improve the depth and quality of OCT imaging. This study thoroughly examines the principles, implementation methods, benefits, and limitations of these techniques. In addition, this study compares the performances of different depth-of-focus extension methods in the contexts of free-space and endoscopic OCT. Finally, this paper offers insights into future developments in depth-of-focus extension techniques for OCT, highlighting promising research directions and potential challenges.
    Chengfu Gu, Haoran Zhang, Qi Lan, Weiyi Zhang, Chang Liu, Jianlong Yang. Advances in Depth-of-Focus Extension Methods for Optical Coherence Tomography[J]. Laser & Optoelectronics Progress, 2024, 61(20): 2011018
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