Excited with three femtosecond laser pulses, the stimulated photon echo phenomenon is studied, which is induced by the optical transition of 1se1sh excitons in a core-shell CdSe/ZnS quantum dot-quantum well. The energy eigenvalues and eigenfunctions of charge carriers were obtained by solving the stationary Schrdinger equation under the effective-mass approximation. The parameter dependence of the photon echo signals was investigated employing the optical Bloch equations. The numerical results reveal that the stimulated photon echo phenomenon can be effectively controlled by the variation of the size and structure of quantum dot-quantum well. And the corresponding mechanism was discussed in terms of the quantum size confined effect theory.