The Al2CrFeCoCuNixTi high entropy alloy coating on Q235 steel surface is prepared by laser cladding. Its microstructure is analyzed, and its mechanical property and corrosion resistance are tested. The results show that the microstructure of cladding zone in the Al2CrFeCoCuNixTi high entropy alloy coating is mainly composed of equiaxed grains with distribution of precipitates. The phase structure of this coating is mainly composed of face-centered-cubic structure, body-centered-cubic structure and Laves phase. With the increase of Ni content, the relative wear resistance of this coating increases first and then decreases with a value of 2.0-3.6. The wear resistance of this coating is affected by both plasticity and hardness. The coatings have excellent corrosion resistance in the 0.5 mol/L H2SO4 solution, and the difference of corrosion resistance mainly depends on the structural components of coatings.