A customized optimization model of phase plate for Extended Depth of Field (EDOF) is introduced based on the various requirements of different EDOF optical imaging system. The requirements contain customized DOF,resolution and minimum Modulation Transfer Function (MTF) value. In the optimization model,insure that the related MTF values is bigger than the minimum MTF value,and the integration of the Fisher information of the Optical Transfer Function (OTF) in the designed range is employed as the optimization target function. Then we optimize the cubic phase plate of the wavefront coding system and the exponential phase plate for several practical requirements. The subsequent image restoration filter is also introduced in the paper. The results show that the combination of the customized phase plate from the optimization model and the restoration filter can meet the requirements of system. And the whole MTF of the system is near the diffraction-limited system’s MTF.