Based on the method of squashing presetting on the high temperature alloy to prepare NiCoCrAlY coating by laser cladding, the influence of squashing treated by cold isostatic pressing on the bonding interface is discussed. The research shows that macroscopic morphology of layers with pretreatment is complete and continuous and the phenomena of cracks in the coating interface are eliminated or reduced. With further study of mechanism, it is found that the thickness of the squashing decreased while the density and laser specific energy required for laser cladding increase, which are beneficial to the quality of interfacial morphologies of laser cladding.