Herein, selective laser melting technology is applied to preparing block samples of multiple sets of GH4169 by changing the laser power and adjusting the scanning speed. The power density of the block samples is calculated, the relative density of the prepared samples is measured, and pores and microstructures of the samples are also observed. Results show that, at a very low scanning speed, the microstructural view of the samples shows circular pores, whereas at a very high scanning speed, irregular shaped pores appear on the microstructure. The parameters suitable for the scanning process include a scanning speed of 0.9-1.5 m/s and the laser power of 260-350 W, samples having higher relative density and lesser pores can be formed, and the highest relative density is 99.7%. The microstructural morphology of the samples with high relative density is in the form of columnar dentrites. As the energy input density increases, there is a gradual refinement in the dendrite growth as well as in the stability.