Diverse spatial mode bases can be exploited in mode-division multiplexing (MDM) to sustain the capacity growth in fiber-optic communications, such as linearly polarized (LP) modes, vector modes, LP orbital angular momentum (LP-OAM) modes, and circularly polarized OAM (CP-OAM) modes. Nevertheless, which kind of mode bases is more appropriate to be utilized in fiber still remains unclear. Here, we aim to find the superior mode basis in MDM fiber-optic communications via a system-level comparison in air-core fiber (ACF). We first investigate the walk-off effect of four spatial mode bases over 1-km ACF, where LP and LP-OAM modes show intrinsic mode walk-off, while it is negligible for vector and CP-OAM modes. We then study the mode coupling effect of degenerate vector and CP-OAM modes over 1-km ACF under fiber perturbations, where degenerate even and odd vector modes suffer severe mode cross talk, while negligible for high-order degenerate CP-OAM modes based on the laws of angular momentum conservation. Moreover, we comprehensively evaluate the system-level performance for data-carrying single-channel and two-channel MDM transmission with different spatial mode bases under various kinds of fiber perturbations (bending, twisting, pressing, winding, and out-of-plane moving). The obtained results indicate that the CP-OAM mode basis shows superiority compared to other mode bases in MDM fiber-optic communications without using multiple-input multiple-output digital signal processing. Our findings may pave the way for robust short-reach MDM optical interconnects for data centers and high-performance computing.