To meet the requirements of laser detection， Tongji University established a full link R & D platform for a precision opto-mechanical system encompassing optical design， structural design， component manufacturing， assembly and adjustment integration， performance evaluation and application after more than ten years of construction. For the development of complex optical and mechanical systems， an efficient coupling comprehensive design method of optical， structural， and thermomechanical design has been developed， a precision assembly integration method based on optical and mechanical error decomposition has been established， a high-precision integrated assembly process and technology for the centering and adjustment of transmission optical systems and reflection optical systems have been formed， and optical system wavefront and imaging performance testing instruments have been equipped， which supports the development of precision optical and mechanical systems with various complex functions. This study comprehensively reviews research on the development of precision opto-mechanical systems and instruments for laser detection. To meet the detection requirement of China's XG-III strong laser facility， the first active and passive composite diagnostic device combining VISAR and SOP and a radiation high temperature optical measurement system are developed， which together provide technical support and diagnostic testing for XG-III to conduct the experiment of ultra-high pressure equation of state. To meet the requirements of measuring the laser scattering characteristics of targets and environments in a sea environment， diffused light and dual function parallel light LRCS laser measuring devices， which can accurately measure the laser scattering characteristics of standard scatterers and sea environment in sea environment simulations and provide mathematical models and experimental data for the development of ultra-low altitude lidar， have been developed.