Since the specific capacity of silicon monoxide anode material (SiOx) has nearly four times greater than that of graphite, it is thus considered as the most promising next-generation anode material for full commercialization of Li-ion batteries. However, the problem of low initial Coulomb efficiency (ICE) has long plagued the application of SiOx. Pre-lithiation can increase the ICE of SiOx and improve the energy density of Li-ion battery systems, paving an effective way for the full-scale application of SiOx. This review represented recent development and application on SiOx anode pre-lithiation. The typical schemes and the corresponding effects were described, and the reaction mechanisms, challenges, and potential solutions were given. In addition, the future development on pre-lithiation technology was also prospected.