In order to explore the computational performance of the existing CIECAM02 and CIECAM16 color appearance models on the color vision differences of individual observers, five lighting sources with different spectral power distribution and 24 colors of the GretagMacbeth ColorChecker standard color card are selected, and 208 sets of individual observer color matching functions are used. The color vision difference of individual observers is quantified. For all selected lighting sources and color centers, the average value of CIECAM-UCS color difference of individual observer and standard observer CIE1964 is the same, which is 1.29. At the same time, in the two color appearance models, the observer variability(the mean color difference from the mean) is relatively consistent, and the observer variability under the white LED light source is relatively large. In addition, the maximum value at color patch blue is 2.49 (2.32). It suggested that the individual differences were larger in this observation condition. The results can provide some basic data and calculation basis for the optimization of color appearance model.