• NUCLEAR TECHNIQUES
  • Vol. 48, Issue 2, 020302 (2025)
Jinpeng HAN1,2, Xingtao AN1, Ji WANG2,*, Zhijun YANG2..., Peiwei WANG2, Jinjie WU2 and Kun WANG2|Show fewer author(s)
Author Affiliations
  • 1Hebei University of Science and Technology, Shijiazhuang 050018, China
  • 2National Institute of Metrology, Beijing 100029, China
  • show less
    DOI: 10.11889/j.0253-3219.2025.hjs.48.240236 Cite this Article
    Jinpeng HAN, Xingtao AN, Ji WANG, Zhijun YANG, Peiwei WANG, Jinjie WU, Kun WANG. Simulation study on the dosimetric parameters of domestically produced high-dose-rate brachytherapy 192Ir source[J]. NUCLEAR TECHNIQUES, 2025, 48(2): 020302 Copy Citation Text show less

    Abstract

    Background

    High dose rate (HDR) brachytherapy is a widely utilized treatment modality in modern clinical brachytherapy. In clinical practice, accurate dosimetric parameters for 192Ir HDR brachytherapy sources are essential. Due to the variation in source designs, each model requires specific dosimetric parameters. Although there is extensive international research on the dosimetric parameters of 192Ir sources, simulation studies focusing on the dosimetric parameters of HDR 192Ir brachytherapy sources produced by the Atomic Hi-Tech (HTA) Co., Ltd are relatively scarce in China.

    Purpose

    This study aims to calculate the dosimetric parameters of a domestically produced HDR 192Ir source by constructing a detailed structural model of the source using Monte Carlo simulation software, based on the dosimetric calculation methods recommended in the TG-43U1 report by the American Association of Physicists in Medicine (AAPM).

    Methods

    Based on the dosimetric calculation methods recommended in the TG-43U1 report by the American Association of Physicists in Medicine (AAPM), Monte Carlo software was used to simulate the 192Ir brachytherapy source, and a detailed structural model of the domestically produced high dose rate 192Ir brachytherapy source was established within the Monte Carlo software to accurately conduct the simulation. Then, the dosimetric parameters calculated in the simulation such as the dose rate constant, air kerma strength per unit activity, radial dose function, and anisotropy function were calculated in the simulation and compared with that reported in the literature.

    Results

    Simulation results show that the simulated dose rate constant is found to be 1.105 cGy·h-1·U-1, with a difference of less than 1.2% compared to values reported in the literature. Additionally, the air kerma strength per unit activity is calculated to be 9.788×10-8 U·Bq-1, with a discrepancy of 0.23% compared to the literature values. Furthermore, the dosimetric parameters for the radial dose function and anisotropy function obtained in this study show a high degree of consistency with corresponding data from existing literature.

    Conclusions

    The domestically produced 192Ir source model established using the Monte Carlo software demonstrates good consistent dosimetric parameters with the literature-reported dosimetric parameters, indicating that this model can be used for clinical practice applications of domestically produced 192Ir sources and has certain guiding significance.

    Jinpeng HAN, Xingtao AN, Ji WANG, Zhijun YANG, Peiwei WANG, Jinjie WU, Kun WANG. Simulation study on the dosimetric parameters of domestically produced high-dose-rate brachytherapy 192Ir source[J]. NUCLEAR TECHNIQUES, 2025, 48(2): 020302
    Download Citation