The fabrication and characterization of microsphere resonators was researched based on an arsenic-free chalcogenide glass whose composition can be represented as: Ge28Sb12Se60. Bulk Ge28Sb12Se60 glasses was fabricated and then crushed into powders. Glass powders were fed into a self-developed furnace and were melted into liquid forms. Molten glass powders were transformed into microspheres due to surface tensions and were cooled/collected in the output of the furnace. Microsphere fabricated in our lab have diameters ranging from 50~200 μm. Two microspheres with diameters of 112.01 μm and 57.63 μm were selected for near field coupling experiments with silica fiber tapers. The microsphere/fiber taper coupling system with a narrow-bandwidth tunable laser was pumped and the spectra of the coupling system for the spectral range of 1 530~1 560 nm was measured. Periodically spaced absorption peaks were clearly noted in the measured spectra, which were attributed to optical resonances happened in corresponding wavelengths due to whispering gallery modes. The spacings of adjacent absorption peaks are 5.22 nm and 2.60 nm for the 112.01 μm and 57.63 μm spheres, which are in good accordance with spacings of first-order WGMs calculated with the classic Mie scattering theory. According to the experimental results, Ge28Sb12Se60 glass can be used as a promising alternative to conventional Arsenic-based chalcogenide glasses for fabricating infrared microsphere resonators, which have important applications in the fields of narrow-bandwidth filters, Raman lasers, and high sensitivity optical sensors.