To explore the application prospects of high-entropy carbide ceramics as wear-resistant parts, a high-entropy (TiVTaMoW)C ceramic with a uniform distribution of elements was prepared via ball milling and subsequent two-step sintering with metal carbides as raw materials. The friction and wear properties of (TiVTaMoW)C ceramic at room temperature and 800 ℃ sliding against Al2O3, SiC, and Si3N4 balls were investigated, respectively. The results show that (TiVTaMoW)C ceramic exhibits superior tribological properties with low friction coefficients and wear rates at room temperature. Especially for sliding against SiC ball, the friction coefficient and wear rate are (0.38±0.01) and (1.52±0.36)×10-7 mm3/(N·m). The surface of (TiVTaMoW)C ceramic is severely oxidized during sliding and accompanied by aggravated wear when the temperature is 800 ℃. The wear rates of high-entropy carbide ceramic sliding against all of the friction pair balls can increase to 10-4 mm3/Nm. The oxidation products of MoO3 and V2O5 with low shear stress characteristics form self-lubricating and transferring films between the friction pairs, which made the friction coefficients maintain the same level as that at room temperature. In addition, SiC friction pair presents better tribological compatibility with (TiVTaMoW)C ceramic with a low friction coefficient and wear rate at room temperature and 800 ℃.