In order to improve the contamination resistance of optical lens surface,the new anti-oil fluorine material which contains organic indium-tin oxide, thin film material, TiAl alloys and SiO2 were chosen as coating materials. Film system was designed by the aid of TF-Calc software. The films were prepared by vacuum coating equipment and ion beam assist deposition. The results of experiments showed that in different vacuum degree and different film thickness the performance of anti-oil also different. The functional of anti-oil were tested through experiments and the process parameters of deposition were constantly optimized. The average reflectivity of the broadband antireflection coating is below 1% over the wavelength range from 350 to 700 nm. The film is hydrophobic, oleophobic, antifouling, and has high firmness and radiation protection ability, which can be used in various fields such as military, medical and civilian.