Out-of-plane displacement of deformation object can be measured by application of vortex beams in electronic speckle pattern interferometry. The deformation measurement was based on the combination of traditional electronic speckle interferometry techniques and liquid crystal spatial light modulators. The vortex beams which were generated by liquid crystal spatial light modulator can be used as reference light or object light. When the vortex beam as reference light and plane beam as object light, or the interference intensity was calculated, and the interference fringe patterns were simulated before and after the tested object deformed. The deformed interference fringe patterns were analyzed and the corresponding phase-maps were calculated though phase shifting method. The three-dimensional phase distribution of simulation is coincident with the theoretical value of out-of-plane displacement. The results show that the vortex beam can be used in out-of-plane displacement measurement, which provides a new method in deformation measurement.