The approach for homogeneous core structure design and selection based on low crosstalk, low dispersion, and acceptable mode effective area have been explored. The forward and backward crosstalk behaviors with respect to wavelength, fiber bending radius, and twisting rate in 12-core, and 21-core single-mode trench-assisted homogenous multicore fiber have been analyzed. The new expression for forward crosstalk under bending and twisting conditions has been derived using the conventional method. For the analysis and optimization of crosstalk, three different core structures are considered, it helps to draw the attention to select the appropriate core structure model for multicore fiber, which follows the standards used in telecom services.