With finite element method,a hexagon High Birefringence Photonic Crystal Fiber (HB-PCF) with two zero-dispersion dots and CdSe/ZnS quantum dots film was designed.The dispersion and loss characteristics of the designed HB-PCFs with the different thickness of CdSe/ZnS quantum dots films were analyzed.The results show that HB-PCFs with CdSe/ZnS quantum dots films exist the fundamental modes along the x- and y-axes of fibers.As pump wavelength increases,the birefringence of HB-PCFs with the same thickness of CdSe/ZnS quantum dots films increases gradually.And their dispersions increase first and then decrease along the x- and y-axes of fiber.The losses of HB-PCFs are close to zero in the visible region while they increase gradually in the infrared region.For the different thickness of CdSe/ZnS quantum dots films,the birefringence of HB-PCFs decreases gradually with the increase of quantum dot film thickness for the same pump wavelength.Their dispersions decrease gradually along the x- and y-axes of fiber,and their two zero-dispersion dots are close to each other,and their losses increase gradually.These research results indicate that the dispersions and losses of the HB-PCFs can be controlled effectively in experiment by depositing the different thickness of CdSe/ZnS quantum dots films and choosing a suitable pump wavelength.