Dynamic simulation process of line of sight between bomb and target in the high frequency laser jamming test on hardware in the loop system for laser guided weapon countermeasure is researched, and the whole process of simulation precision analysis of line of sight between bomb and target is proposed. Then the geometric error，control error and optical assembling error, which influence the simulation precision, are analyzed in total, the error model of line of sight between bomb and target is set up by adopting multi-body error analysis theory. Experimental testing method of simulation error of line of sight between bomb and target is designed, and the unknown error in the error model is identified by means of actual test combined with error modeling. The simulation accuracy analysis of line of sight between bomb and target is proposed using Monto-Carlo mothod or residual analysis, and the estimated value and its variation are calculated.