Free-space quantum key distribution (QKD) allows two distant parties to share secret keys with information-theoretic security, which can pave the way for satellite-ground quantum communication to set up a global network for sharing secret message. However, free-space channels in the presence of atmospheric turbulence are affected by losses and fluctuating transmissivity which further affect the quantum bit error rate and the secure key rate. To implement free-space QKD, it is indispensable to study the effect of atmospheric turbulence. Different models have been used to describe the probability distribution for channel transmission coefficient under atmospheric turbulence, including the log-normal distribution and K distribution. In this paper, we focus on free space measurement-device-independent quantum key distribution (MDI-QKD) under K-distributed strong atmospheric turbulence. The MDI-QKD can close all loopholes on detection and achieve a similar performance to QKD, relying on time-reversed version of entanglement-based QKD protocol. Threshold post-selection method is adopted to restrain detrimental effects of the atmospheric turbulence, which is based on the selection of the intervals with higher channel transmissivity. By combining the general MDI-QKD system model with this method, we present a framework for the optimal choice of threshold. Our simulation result shows that the optimal threshold is dependent on the turbulence intensity and expected channel loss. Furthermore, compared with the original MDI-QKD protocols, the proposed protocol with threshold post-selection method can acquire a considerable better performance in key rate, especially in regions of high turbulence and high loss. What is more, this is instructive to the building of a practical free-space MDI-QKD system with better performance.