The trace elements of Compound paracetamol and amantadine dispersible tablets, Compound paracetamol and alkylamine tablets (Gankang) and Four seasons cold tablets have been analyzed by Laser-induced Breakdown Spectroscopy (LIBS). The laser with wavelength of 532 nm was focused on the surface of the medicine tablets to generate plasma, and then the spectra of the cold medicine tablets were detected through the collection of optical fiber and spectrometer, and the spectrograph of ICCD. The optimum spectra were obtained by optimizing the acquisition delay and gate width of ICCD. The results show that trace elements of Ca, Mg, Na have been identified in the Compound paracetamol and amantadine dispersible tablets and Four seasons cold tablets, and Ca, Mg have been identified in the Compound paracetamol and alkylamine tablets (Gankang). The electron temperature of plasma were calculated from the intensity of emission spectrum, the excitation energy, statistical weight of the upper levels and the corresponding transition probability of emission spectra. Then the time evolution characteristics of the electron temperature of the plasma induced by laser for the three kinds of cold tablets were studied.