In response to the therapeutic challenges of Acute Ischemic Stroke (AIS), a wireless power supply system for sphenopalatine ganglion electrical stimulation has been designed to address the limitations of traditional treatment. By employing near-field magnetic resonance coupling technology and an S-S topology with constant current characteristics, a stable current supply is provided. To ensure stable transmission at a constant frequency, the coil coupling is controlled near the critical coupling point to suppress the frequency splitting effect. The system uses a receiving coil with a diameter of 10 mm, achieving a Power Transfer Efficiency (PTE) of 25% in air and 12% in biological tissue, and maintaining over 90% of the alignment efficiency when the receiving coil deviates from the center of the transmitting coil by 5 mm, demonstrating good misalignment tolerance. This innovative solution is expected to meet the power supply needs of sphenopalatine ganglion electrical stimulation instruments, offering new possibilities for the treatment of AIS.