In order to solve the problems that the structure of existing explosion point spatial location detection system was complex and the cost was expensive, a simulation research was carried out which was on instantaneous position measurement of explosion point based on the general industrial camera. The LED transient flash unit was designed, and the photoelectric sensor detected the light signal generated by the LED and converted it into an electrical signal. After signal processing, the two general industrial cameras were controlled to expose and capture at the same time according to the signal amplitude. The collected images were digitally processed to obtain the position coordinates of center of explosion spot in two images, and then combined with the relative position relationship between two cameras, the spatial location coordinates of explosion point were finally calculated. The experimental results show that at 24 m, 32 m, and 48 m from the measuring system, the absolute maximum error in the horizontal direction $X$ is 127 mm, in the vertical direction $Y$ is 68 mm, and in the depth direction $Z$ is 279 mm. The system has the advantages of fast response speed, high precision, low cost, and etc, which meet the requirements of system detection.