Based on the principle of laser measurement and the characteristics of micronano cameras, a new inorbit pointing calibration method for micronano remote sensing cameras are investigated. This method adopts optical path and focal plane multiplexing technology to realize integration of calibration device and camera system. Through this method, realtime calibration on each scene remote sensing image becomes possible. This paper verifies this new method of inorbit pointing calibration using one new micronano remote sensing camera. Simulation results show that the optical axis pointing calibration accuracy does not exceed 0.2″, which satisfies the requirements of the camera image, controlling the plane positioning accuracy within 30 m. Through the preparation and calibration results of principle prototype, the principle and practical feasibility of this method are further proved. This method can help improving the quantitative application value of micronano remote sensing satellites.