Commercial thermodynamic calculation software FactSage plays an important role in the analysis of slag corrosion process，therefore it has been widely used in the research of refractories. Application of thermodynamic calculation on slag corrosion resistance of refractories and thermodynamic calculation models which are commonly used in the slag corrosion resistance of refractories were introduced. The mechanisms, characteristics, applicable situations, accuracy and limitations of every model were discussed, and the detailed examples were given. Furthermore, the application examples of FactSage combined with other methods including ANSYS, kinetic analysis and MD simulation were given, aiming to avoid the limitations of thermodynamic calculation and comprehensively analyze the slag corrosion behavior. Lastly, the common problems of thermodynamic calculation were summarized, and the direction of further development was proposed.