A novel algorithm is proposed and designed to route and process the optical signals of a crossover network.Firstly, based on the link rule and function principle of the crossover network, the corresponding processing matrixes are achieved to denote and illustrate the relative signal operating and control and to establish the relation between input and output signals.According to the performing matrixes and the orders of input/output signal arrays, the node controlling and signal routing are determined.Finally, the signals are routed and controlled.It is shown that the proposed algorithm can not only be used in the routing control for a 8×8 crossover optical interconnection network,but also can be used in those for 16×16,32×32 and 64×64 networks.Furthermore,it also has excellent transplant ability and compatibility for perfect shaffle networks and Banyan networks.These results indicate that the routing algorithm is useful for optical switching applications, optical computing, and optical information processing in the future.