To overcome the restrictions of long calibration time, high cost and poor maneuverability for radiometric calibration of the ground-based infrared radiometric measurement systems with large aperture, a radiometric calibration method, which is based on low-temperature area blackbody, for infrared systems with high dynamic range was proposed. First of all, the neutral-density filter in the system was measured to obtain its actual transmissivity and calculate its radiance. Secondly, the radiometric calibration was performed using low-temperature blackbody at two integration times. The response and stray radiation of the system as well as the bias of the detector were obtained on the basis of the calibration results. Then, the calibration results at high dynamic range could be acquired by extrapolating the low-temperature calibration results, combined with the measured characteristics of the neutral-density filter. To verify the effectiveness of the proposed method, a Φ600mm infrared system was calibrated at high dynamic range, using the proposed method and the typical method of high-temperature blackbody and large aperture collimator. The experimental results indicate that the error of the proposed method is less than 10.25%, which means the proposed method can be used to perform calibration for the system. The radiometric calibration for infrared systems with high dynamic range can be achieved only with a low-temperature blackbody in the outfield. The proposed method, with the advantages of simple operation and strong real-time, has a value for application.