In order to design a high frame,large array driver circuit which supports electronic image motion compensation funcition, meet the fuction of image motion compensation.First,the basicdriver circuit of the large array CCD FTF5066M was given,and added an "image motion compensation timing generator whick worked together with the main timing generator SAA8103 was added to achieve the electronic image motion compensation. Then the internal structure of the "image motion compensation timing generator" was given ,the additonal image motion compensation timing generator was only used to produce the vertical transfer drive timing, timing signals and tranfer the timing sigals produces by SAA8103. The FPGA as the image motion compensation timing generator was selected, and the timing simulation was done. In the end, indoor experiment of image motion compensation was given to test the driver circuit designed.The good compensation effect was achieved. The driving circuit system supported a maximum frame rate up to 2.7 F/s, signal to noise ratio reached 66 dB. This driver-circuit can conveniently select output channel number and output mode, the camera is suitable for different occasions.