Si-qian SHI, Fang-wei YANG, Wei-rong YAO, Hang YU, Yun-fei XIE. Rapid Detection of Levamisole Residue in Pork by Surface Enhanced Raman Spectroscopy[J]. Spectroscopy and Spectral Analysis, 2021, 41(12): 3759

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- Spectroscopy and Spectral Analysis
- Vol. 41, Issue 12, 3759 (2021)

Fig. 1. Chemical structural formula of levamisole

Fig. 2. Theoretical calculation results of levamisole hydrochloride
(a): Optimize molecular structural formula of levamisole hydrochloride; (b): Comparison between theoretical Raman spectra and solid Raman spectra
(a): Optimize molecular structural formula of levamisole hydrochloride; (b): Comparison between theoretical Raman spectra and solid Raman spectra

Fig. 3. SERS peak intensity at 469 cm-1 under different detection conditions

Fig. 4. SERS spectra of levamisole hydrochloride in methanol solution with different concentrations
a —j , solid, methanol, 0.01, 0.1, 1, 10, 75, 100, 250, 500 mg·L-1 solution respectively

Fig. 5. Linear relationship between peak intensity and concentration

Fig. 6. Comparison of extraction effects of different extraction methods
a : Solid; b : Once liquid-liquid extraction blank; c : Once liquid-liquid extraction standard addition; d : Twice liquid-liquid extraction blank; e : Twice liquid-liquid extraction standard addition

Fig. 7. Comparison of extraction effects of different extraction solvents
a : Solid; b : Ethyl acetate blank; c : n-hexane blank; d : Chloroform blank; e : Ethyl acetate extraction; f : n-hexane extraction; g : Chloroform extraction

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