In order to realize the effective evaluation of the effect of laser angle deception, the laser angle deception interference effect evaluation system was constructed, and the structure and function of the target motion simulation subsystem, the laser guided missile simulation sub-system and the interference effect evaluation subsystem were introduced in detail. Combined with the interference effect evaluation method, the relevant experiment was designed. Through the detailed analysis of the experimental data, the interference effect was evaluated. In the experiment, when the laser pulse period was 50 000 microseconds, the interference laser was set up 2, 3, 4, and -3 microseconds ahead of guidance laser, and the solutions of point deviations were 154.14, 167.03, 174.93, and 0.52 meters respectively; When the laser pulse period was 51 200 microseconds, the interference laser was set up 2, -2, and 3 microseconds ahead of guidance laser, and the solutions of point deviations were 396.86, 0.53, and 396.86 meters respectively. The results show that the interference of the pilot emitter can be achieved when the interference pulse leading pulse enters the seeker gate simulator. Through this experiment, it was found that the seeker simulator tracks the interference of laser spot itself in laser angle deception interference, rather than the interference laser and indicating the laser energy center. The deviation of the placement point for the assessment of indicators, the interference effect were evaluated and analyzed, and the results can provide technical support for laser guidance and confrontation evaluation.