The six heavy metal concentrations (Cr, Cr, As, Cd, Cu, Zn and Pb) in water samples collected from five reservoirs of Liao River Basin were studied. The health risk assessment for heavy metals pollution in reservoirs was conducted based on the environmental health risk assessment model recommended by U. S. Environmental Protection Agency. The results showed that the average concentrations of Cr, Cu, Zn, As, Cd and Pb in five reservoirs of Liao River Basin were 3.36, 1.03, 2.70, 1.23, 0.02 and 0.03 μg·L-1, respectively. In fact, these heavy metals concentrations were obviously lower than the Standard of National Drinking Water in China (GB 5749—2006). The results also showed that the metal carcinogenic risk was relatively high in this region. The order of the risk level of carcinogenic metals was Cr>As>Cd. The highest carcinogenic risk was from Cr, with the risk for adults ranging from 4.50×10-5~7.53×10-5 a-1 and the risk for children ranging from 6.29×10-5 to 1.05×10-4 a-1. The health risk levels caused by non-carcinogenic metals ranging from 10-13 to 10-10 a-1 were lower than the acceptable range suggested by International Commission on Radiological Protection (ICRP) and the order of the risk level of non-carcinogenic metals was Cu>Zn>Pb. The total health risk of heavy metals for adults ranging from 1.07×10-4 to 1.72×10-4 a-1 and for children ranging from 1.49×10-4 to 2.40×10-4 a-1 exceeded the accepted level of 5×10-5 a-1 as suggested by ICRP. The health risk levels of carcinogenic metals were significantly higher than those of non-carcinogenic metals in the reservoirs for Liao River Basin.