In order to study a deep hole blasting dispose technology for blind goaf with large volume, large roof thickness and limited space, the 49-590 large-scale goaf in Dabaoshan open-pit mine was taken as an engineering example in this research.The goaf parameters were obtained by a 3D laser scanning system C-ALS and 3D solid modeling technology.The minimum safety thickness the roof was calculated to determine the best time for goaf treatment by using traditional mechanical method, limit analysis method and theory of elastic thin sheet with small deformation.By integrating the detection parameters of the goaf and the calculation results of the minimum safety thickness the roof, a reasonable blasting caving scheme for the goaf was adopted.The cut area was set in the thinnest part of the roof and the local powder factor was increased.Meanwhile, the bottom-charging hole was designed in the cut area to obtain the blasting compensation space.Thus, the goaf was effectively blasted.Using the volume balance method to evaluate the blasting effect, the roof was completely collapsed, and an expected effect was achieved.