High-performance optical limiting (OL) is of great importance in laser protection application. Although the research of OL lasts for decades, most existing material can not possess all the desired merits such as low threshold, high linear transmittance, especially broadband and ultrafast respondence. Here, the multi-functional OL in conjugated twistacene was reported through experiments and theory. Results show that broadband OL with fast switching speed can be achieved from 480 nm-700 nm based on effective three-photon absorption. Moreover, low OL thresholds (0.15 J/cm2) and extremely high linear transmittance (92% at 532 nm) are simultaneously observed. All these combined advantages in one material shows tremendous potential in ultrafast laser protection for human eye and photonic devices.