In order to find out rule of sintering temperature of hydroxyapatite(HA) target, the powder of 99% pure hydroxyapatite was pressed to discal targets and the targets were sintered at 600
C, 700
C and 800
C in argon ambience respectively. The targets stinered at different temperatures and the targets not sintered were detected with X-ray diffractometer(XRD) and the X-ray photoelectron spectroscopy(XPS). The experimental result demonstrates that sintering temperature does not influence on the composition and crystallinity of all kinds of targets observably, but the average particle diameter and the ratio of Ca to P of hydroxyapatite targets should increase if sintering temperature rise. The hydroxyapatite target sintered at 800
C has the best biocompatibility, bioactivity and stability.