Sensitivity analysis of cable crosstalk to uncertain parameters is studied using stochastic reduced order model (SROM), and then the uncertainty of cable crosstalk is predicted. To verify the prediction, a three-conductor transmission line (TL) experiment system is established. Both near end and far end crosstalk (NEXT and FEXT) are tested. Then the measurement uncertainty is deduced according to the standard GB/Z 6113.401—2018/CISPR/TR 16-4-1:2009. Comparing the predicted uncertainty to the measured one, it is found that they have the same variation trends with frequency. Moreover, the measured uncertainty is within the range of the prediction. Therefore, the uncertainty prediction using SROM can be applied to predict the test uncertainty, which is instructive to the crosstalk measurement for both analysis model verification and experimental investigation.