The paper aims to enhance the cultivation of innovative practical skills in university students and conducts a comprehensive experimental research on the course of Basic Principles of Concrete Structures. The study designs and implements a comprehensive experiment on the bond behavior of reinforcement and concrete, covering concrete compressive strength, pull-out test of reinforcement from concrete, analysis of factors affecting bond strength, and examination of reinforcement slip. Through these teaching contents, students’ understanding, mastery, and flexible application of professional knowledge are reinforced, while their practical and innovative abilities are elevated. The practical application of experimental teaching demonstrates that this comprehensive approach effectively improves the teaching outcomes, and students have provided positive feedback. This research offers valuable insights for the construction of new engineering disciplines in universities and the cultivation of students’ innovative practical skills.