Yutong ZHU, Peijie TAN, Hai LIN, Xiangdong ZHU, Xingdong ZHANG. Injectable Hyaluronan/Hydroxyapatite Composite: Preparation, Physicochemical Property and Biocompatibility [J]. Journal of Inorganic Materials, 2020, 36(9): 981
- Journal of Inorganic Materials
- Vol. 36, Issue 9, 981 (2020)
1. Diagram of reaction between HA and BDDE
2. Appearance of composite hydrogels before and after autoclaving
3. Appearance of composite hydrogels HAP45-1.0 with remained crosslinking reagents
4. Storage modulus (a), loss modulus (b) and composite viscosity (c) of hydrogels before and after sterilization
5. SEM morphologies of hydrogels
6. Push-out strain-stress curves of hydrogels
7. Swelling behavior of composite hydrogel HAP45-1.0 and stabilization in vitro
8. Enzymatic degradation of composite hydrogel HAP45-1.0 in vitro by HAase at 120 U/mL
9. Fibroblast adhesion after being seeded on the surface of hydrogels observed by confocal fluorescence microscope
10. Proliferation of fibroblasts on surface of hydrogels (*p <0.05)
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Table 1. Amount of HA, HAP and BDDE in preparing composite hydrogels
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Table 2. Contents of HA and HAP in different composites before and after dialysis
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Table 3. The 1st order exponential decay equation fitting results of hydrogel HAP45-1.0 swelling behavior
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