• Laser & Optoelectronics Progress
  • Vol. 61, Issue 6, 0618001 (2024)
Wang Ma1,2, Jia Qian1, Siying Wang1, Rui Ma1..., Xing Li1, Shipei Dang1, Xing Li1, Chen Bai1,2, Dan Dan1,2,* and Baoli Yao1,2,**|Show fewer author(s)
Author Affiliations
  • 1State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, Shaanxi, China
  • 2University of Chinese Academy of Sciences, Beijing 100049, China
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    DOI: 10.3788/LOP240550 Cite this Article Set citation alerts
    Wang Ma, Jia Qian, Siying Wang, Rui Ma, Xing Li, Shipei Dang, Xing Li, Chen Bai, Dan Dan, Baoli Yao. Recent Advances in Super-Resolution and Optical Sectioning of Digital-Micromirror Device-Based Structured-Illumination Microscopy (Invited)[J]. Laser & Optoelectronics Progress, 2024, 61(6): 0618001 Copy Citation Text show less
    The principle of spectrum expansion in SIM. (a) The overlapping of the sample and the illumination patterns produces low-frequency Moiré fringes through frequency beating; (b) the expansion and fusion of the sample spectrum under structured illumination along one single orientation; (c) the isotropic expansion and fusion of the sample spectrum under structured illumination along three orientations
    Fig. 1. The principle of spectrum expansion in SIM. (a) The overlapping of the sample and the illumination patterns produces low-frequency Moiré fringes through frequency beating; (b) the expansion and fusion of the sample spectrum under structured illumination along one single orientation; (c) the isotropic expansion and fusion of the sample spectrum under structured illumination along three orientations
    The principle and flowchart of spatial domain reconstruction of SR-SIM image[23]. (a) Schematic diagram of the PSF compression in SDR; (b) the PSF's FWHM value variation with the spatial frequency of the illumination fringes; (c) the comparison of SDR and FDR workflow
    Fig. 2. The principle and flowchart of spatial domain reconstruction of SR-SIM image[23]. (a) Schematic diagram of the PSF compression in SDR; (b) the PSF's FWHM value variation with the spatial frequency of the illumination fringes; (c) the comparison of SDR and FDR workflow
    Principle of the super-resolution and optical section integrated SIM[41]
    Fig. 3. Principle of the super-resolution and optical section integrated SIM[41]
    Principle of DMD. (a) DMD chip; (b) structure of the DMD micromirror array; (c) illustration of the incident and output light on the DMD; (d) schematic of the incident light modulation in three different states of micromirrors
    Fig. 4. Principle of DMD. (a) DMD chip; (b) structure of the DMD micromirror array; (c) illustration of the incident and output light on the DMD; (d) schematic of the incident light modulation in three different states of micromirrors
    Schematic diagrams of generating structured illumination using DMD projection. (a) Grating projection method; (b) DMD projection method; (c) the conversion from binary periodic square patterns to sinusoidal patterns
    Fig. 5. Schematic diagrams of generating structured illumination using DMD projection. (a) Grating projection method; (b) DMD projection method; (c) the conversion from binary periodic square patterns to sinusoidal patterns
    Typical optical paths for generating structured illumination based on SLM laser interferometry and DMD laser interferometry. (a) SLM[44]; (b) DMD[76]
    Fig. 6. Typical optical paths for generating structured illumination based on SLM laser interferometry and DMD laser interferometry. (a) SLM[44]; (b) DMD[76]
    The model of DMD two-dimensional blazed diffractive gratings and the analysis of diffracted beams[98]
    Fig. 7. The model of DMD two-dimensional blazed diffractive gratings and the analysis of diffracted beams[98]
    The non-paraxial diffraction model of DMD[99]
    Fig. 8. The non-paraxial diffraction model of DMD[99]
    Timeline of DMD-SIM development
    Fig. 9. Timeline of DMD-SIM development
    The setup of LiDMD-SIM[102]
    Fig. 10. The setup of LiDMD-SIM[102]
    Schematic of the hybrid multifocal structured illumination microscope[103]
    Fig. 11. Schematic of the hybrid multifocal structured illumination microscope[103]
    The dual color DMD-SIM microscope[104]
    Fig. 12. The dual color DMD-SIM microscope[104]
    The schematic of three-wavelength DMD-SIM super-resolution microscopy[105]
    Fig. 13. The schematic of three-wavelength DMD-SIM super-resolution microscopy[105]
    The schematic of laser illumination speckle-free DMD-SIM super-resolution microscopy[106]
    Fig. 14. The schematic of laser illumination speckle-free DMD-SIM super-resolution microscopy[106]
    Imaging results of DMD-3DSIM[76]
    Fig. 15. Imaging results of DMD-3DSIM[76]
    The schematic of multi-color DMD-SIM based on grating dispersion compensation[107]
    Fig. 16. The schematic of multi-color DMD-SIM based on grating dispersion compensation[107]
    Full-Color optical sectioning three-dimensional microscopy based on DMD-SIM[108]
    Fig. 17. Full-Color optical sectioning three-dimensional microscopy based on DMD-SIM[108]
    Schematic diagram of the C-SIM system[109]
    Fig. 18. Schematic diagram of the C-SIM system[109]
    Imaging results of HDR-C-SIM[111]
    Fig. 19. Imaging results of HDR-C-SIM[111]
    Fast optical sectioning algorithm of SIM based on Hilbert transform[113]
    Fig. 20. Fast optical sectioning algorithm of SIM based on Hilbert transform[113]
    Configuration of SIMscope3D and its imaging results[7]
    Fig. 21. Configuration of SIMscope3D and its imaging results[7]
    Imaging results of Fourier Domain-based High-Quality SIM optical sectioning reconstruction method[114]
    Fig. 22. Imaging results of Fourier Domain-based High-Quality SIM optical sectioning reconstruction method[114]
    AlgorithmReconstruction domainReconstruction speedReconstruction qualityFeature
    Open-SIM59FDRSlowMiddleEasy to use
    Fair-SIM60FDRSlowLowImageJ plugin
    HiFi-SIM61FDRSlowHighHigh quality
    Hessian-SIM64FDRSlowMiddleFast dynamic imaging
    SDR-SIM23SDRFastHighNo Frequency Domain processing
    EFSD-SIM71SDRFastMiddleEstimation-free
    JSFR-SIM69SDR+FDRFastHighBackground suppression
    Direct-SIM68SDR+FDRFastMiddleEstimation-free
    Table 1. Comparison of different reconstruction algorithms for SR-SIM
    SIM techniqueSI generationImaging speedImaging qualityFeature
    Projection DMD-SIM40ProjectionFastExcellentCompact and low-cost
    Interference DMD-SIM76-77InterferenceFastExcellentSpecific beam incident angle
    Grating SIM19Projection/interferenceSlowModerateLow mechanical control
    SLM-SIM45-46InterferenceFastExcellentComplex polarization control
    Speckle SIM78-81Speckle illuminationSlowModerateLow speed
    TIRF SIM83-85Evanescent wave InterferenceSlowgoodTIRF mode required
    Photonic-chip SIM82Evanescent wave InterferenceMiddlegoodNo illumination objective lens
    Plasmonic SIM86-88SP wave InterferenceMiddlegoodPlasmon required
    Table 2. Comparison of DMD-SIM with other types of SIM
    Wang Ma, Jia Qian, Siying Wang, Rui Ma, Xing Li, Shipei Dang, Xing Li, Chen Bai, Dan Dan, Baoli Yao. Recent Advances in Super-Resolution and Optical Sectioning of Digital-Micromirror Device-Based Structured-Illumination Microscopy (Invited)[J]. Laser & Optoelectronics Progress, 2024, 61(6): 0618001
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