Coronary heart disease (CHD) is a serious complication of hypertension disease (HD). But this complication can not get timely detected, which is likely to cause serious events and result in extremely high disability rates and mortality. Therefore, early screening is important to provide early intervention to prevent the occurrence of serious events. Tongue manifestation can reflect the condition of the heart. In this paper, we applied tongue hyperspectral imaging to the early screen of the HD complicated with CHD patients. Hyperspectral data of 154 samples were collected from the department of cardiology. The wavelength range of hyperspectral data is 377.38~1 049.1 nm. The correlated clinical diagnosis was also recorded. Hyperspectral data of the tongue was separated into five parts according to the Chinese medicine theory, which included tongue tip, tongue left, tongue middle, tongue right and tongue root. There are maximum and minimum values at 509.6, 561.2, 540.5 and 576.7 nm. Moreover, this is consistent with the light absorption characteristics of hemoglobin.Then different tongue parts of the two groups were compared. The T-test results showed that there were significant differences between tongue tip and tongue middle in the wavelength region of 500~600 nm. Backpropagation artificial neural network (BPANN) was employed as an identification method for the screening whether or not complicated with CHD. The optimal results of screening model are obtained with an accuracy of 84.78%, sensitivity of 86.95%, and specificity of 82.61%, respectively. Experiment results showed that there were significant differences between HD and HD-CHD hyperspectral data, and hyperspectral imaging of the tongue provides a possible way for screening HD complicated with CHD among HD patients.