The ultraviolet radiance is primarily influenced by the ozone concentrations in the near space. Besides, the ozone is a strong oxidant and an important source of OH in the near space. It will change the atmospheric physical and chemical property directly and/or indirectly. So, the research on ozone profile with the high spatial and temporal resolutions, accuracy will more effectively address the requirements of applications and principles of atmospheric photochemical.The satellites become the viable options to obtain the ozone profiles in the middle and upper atmosphere and local coverage. The ozone limb payloads begin to age for providing the available observation data at present and a few new missions are planned in the future. So, the retrieval algorithm of ozone profile using the radiance obtained by nadir mode is necessary. The ozone priori profile is an important role in the retrieval algorithm based on the optimization estimation technology. The higher precision of priori, the higher precision of the inversion results. The ability to simulate high spatial and temporal ozone profiles with the Goddard Earth Observing System-Chemistry (GEOS-Chem) model is used to construct high spatial and temporal resolution ozone priori profile information for retrieval algorithm of ozone profile in near space. The ground-based measurements and ozone profile products from limb sensors are used to validate the inversion results.A variety of inversion experiments are conducted, in order to assess the feasibility and accuracy of the a priori ozone profile from GEOS-Chem. On the one hand, a comparison experiment of the two types of inversion results is carried out based on the a priori ozone profile constructed by GEOS-Chem and the TpO3 climatology. The superiority of the results based on GEOS-Chem is demonstrated by comparing them with the ground-based measurements and OMPS_LP ozone profile products in China region at typical time. The R² of GEOS-Chem inversion results are larger than TpO3 inversion results. The TROPOMI Level 2 ozone profile products are selected as the other comparison for further inversion experiments in a wider range of scenarios. The GEOS-Chem inversion results and it are validated and compared with the ground-based measurements and ozone profile products from limb sensors. The only validation measurements of ground-based ozonesonde are the Hong Kong King′s Park stations in the China. The relative difference is used to verified the accuracy of GEOS-Chem inversion results and TROPOMI Level 2 products. The comparison and verification show that the inversion results based on GEOS-Chem model are consistent with the high-precision ground-based measurements. The relative difference between the GEOS-Chem inversion results and ozonesonde measurements are from -5.90% to 37.12%. However, the relative difference between the TROPOMI Level 2 products and ozonesonde measurements are from -9.40% to 52.92 %. These lead to a variation of UV radiation from 1.22×10^-6 to 5.50×10^-6 W·nm^-1·m^-2 in the wavelength of 280.25 nm. Moreover, the GEOS-Chem inversion results and TROPOMI Level 2 product are compared with the OMPS_LP load ozone product in order to obtain the accuracy of the GEOS-Chem inversion results in different altitude areas. In the Xizang regions, the relative difference between the GEOS-Chem inversion results and OMPS_LP Level 2 products are from -31.08% to 39.76%. However, the relative difference between the TROPOMI Level 2 products and OMPS_LP Level 2 products are from -45.55% to 53.93 %. In the Southeast region, the extreme value of relative difference between the GEOS-Chem inversion results and OMPS_LP Level 2 products is 42.11%, and the corresponding value of TROPOMI Level 2 products is 63.02%. The different precision ozone profile results lead to the ultraviolet radiation to change by a maximum of 50.27% and -41.79% approximately in the two regions. The relative differences show that GEOS-Chem inversion results have more accuracy and stability than the TROPOMI Level 2 products.The relative difference between the inversion results based on the GEOS-Chem ozone priori profile and validation data is much smaller than those based on the TROPOMI Level 2 products. The oscillation of the relative differences is smoother than the later. These results show that the accuracy of the GEOS-Chem inversion results can be improved greatly. As the GEOS-Chem model advances and ongoing updates are made to meteorological field data and chemical mechanisms, the accuracy and reliability of ozone profiles derived from its inversion will see enhancement. This improvement opens up the potential for refining ozone inversion accuracy. The change in ultraviolet radiation can be reflected better in the near space.