• Laser & Optoelectronics Progress
  • Vol. 62, Issue 8, 0800004 (2025)
Yuxuan Li1, Yanping Huang2,3, Jingjiang Xu2,3, Jia Qin3..., Lin An3 and Gongpu Lan2,3,*|Show fewer author(s)
Author Affiliations
  • 1School of Mechatronic Engineering and Automation, Foshan University, Foshan 528000, Guangdong , China
  • 2Guangdong-Hong Kong-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology, School of Physics and Optoelectronic Engineering, Foshan University, Foshan 528000, Guangdong , China
  • 3Guangdong Weiren Medical Technology Co., Ltd., Foshan 528000, Guangdong , China
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    DOI: 10.3788/LOP241909 Cite this Article Set citation alerts
    Yuxuan Li, Yanping Huang, Jingjiang Xu, Jia Qin, Lin An, Gongpu Lan. Advances in Linear-Wavenumber Spectral Domain Optical Coherence Tomography[J]. Laser & Optoelectronics Progress, 2025, 62(8): 0800004 Copy Citation Text show less

    Abstract

    Spectral domain optical coherence tomography (SD-OCT) has achieved significant progress in biomedical imaging, particularly in ophthalmology. However, SD-OCT exhibits reduced signal sensitivity in deeper imaging regions compared to swept-source OCT due to the phenomenon of sensitivity roll-off. Linear-wavenumber spectroscopy employs an optical solution to achieve linear spectral splitting in the wavenumber domain, thereby enhancing the system's signal-to-noise ratio in the depth direction. This paper presents a comprehensive overview of the fundamental principles of the SD-OCT system, the spectroscopic theory of linear-wavenumber, the optical model of linear-wavenumber dispersion, and the application of linear-wavenumber SD-OCT in the imaging of soft tissue structures, angiography, and elastography. Although the application market for linear-wavenumber OCT remains relatively small, its ability to improve the signal-to-noise ratio and imaging speed is noteworthy. As the technology continues to advance, linear-wavenumber SD-OCT is expected to play an increasingly significant role in clinical diagnosis and biomedical research.
    I(k)=ρ4SkRr+R1+R2++ρ2Skn=1NRrRncoskXr-Xn+ρ4Sknm=1NRnRmcoskXn-Xm
    Izn=1NRrRnexpπΔλλc2Xr-Xn+exp-πΔλλc2Xr-Xn
    Δz=2ln(2)πλc2Δλ
    Δx=2ln(2)πλcNA
    zmax=λc2N4Δλ
    Fz=sinpRzpRzexp-1+η22Δxc2R2z2
    dsinθi±sinθd=mλ,   m=0, ±1, ±2, 
    δθGδλ=mdcosθd
    RG=λΔλ=λδλδθGΔθ=λdcosθdmλNlinedcosθd=mNline
    θi=arcsinλc2d
    θd=arcsin2λm-λc2d
    δθPδλdndλ1λ3
    RP=λΔλ=λδλδθPλD=δθPδλD
    δ=θ0+β+θ2'-αα=θ1'+θ2
    δ=θ0+β+arcsinnsinα-arcsinsinθ0+βn-α
    δθ0+β+nα-1nθ0+β-α=n-1α
    θ1'=arcsin1n1sinθ1θm+1'=arcsinnmnm+1sinαm-θm'    m=1,2θ4'=arcsinn3sinα3-θ3'
    θd=arcsin2πkmd1-πkcd1
    θd'=arcsin2πkmd2-sinarcsin2πkmd1-πkcd1-σ
    αd=arcsinnsinε-arcsin2πkmnd-πkcnd
    ε=arcsinsinβin+arcsinsinγdn
    βi=βic+θd-θi
    γd=arcsinnsinε-arcsin1nsinβiβi=arcsinncsinε2+arcsin2πkmd-πkcd-arcsinπkcd
    Yuxuan Li, Yanping Huang, Jingjiang Xu, Jia Qin, Lin An, Gongpu Lan. Advances in Linear-Wavenumber Spectral Domain Optical Coherence Tomography[J]. Laser & Optoelectronics Progress, 2025, 62(8): 0800004
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